Selected articles
Epidermal IL-15Rα acts as an endogenous antagonist of psoriasiform inflammation in mouse and man.
French LE, Bouchaud G, Gehrke S, Krieg C, et al.
J Exp Med. 2013; 210(10):2105-17. Impact Factor: 1.355. PMID: 24019554
The Nlrp3 inflammasome regulates acute graft-versus-host disease.
French LE, Jankovic D, Ganesan J, Bscheider M, et al.
J Exp Med. 2013; 210(10):1899-910. Impact Factor: 13.214. PMID: 23980097
Direct presentation of a melanocyte-associated antigen in peripheral lymph nodes induces cytotoxic CD8+ T cells.
French LE, Schuler P, Contassot E, Irla M, et al.
Cancer Res. 2008; 68(20):8410-8. Impact Factor: 7.7. PMID: 18922914
Resistance to FasL and TRAIL-mediated apoptosis in Sézary syndrome T-cells associated with impaired death receptor and cFLIP expression.
French LE, Contassot E, Kerl K, Roques S, et al.
Blood. 2008; 111(9):4780-7. PMID: 18314443
Extralymphatic tumors prepare draining lymph nodes to invasion via a T-cell cross-tolerance process.
French LE, Preynat-Seauve O, Contassot E, Schuler P, Piguet V, Huard B.
Cancer Res. 2007; 67(10):5009-16. Impact Factor: 8.2. PMID: 17510433
Tumor-infiltrating dendritic cells are potent antigen-presenting cells able to activate T cells and mediate tumor rejection.
French LE, Preynat-Seauve O, Schuler P, Contassot E, Beermann F, Huard B,
J Immunol. 2006; 176(1):61-7. PMID: 16365396
Impaired CD40L signaling is a cause of defective IL-12 and TNF-alpha production in Sézary syndrome: circumvention by hexameric soluble CD40L.
French LE, Huard B, Wysocka M, et al.
Blood. 2005; 105(1):219-25. Impact Factor: 10.1. PMID: 15315967
Inhibition of Toxic Epidermal Necrolysis by blockade of CD95 with Human Intravenous Immunoglobulin.
French LE, Viard I, Wehrli P, Bullani R, et al.
Science. 1998; 282(5388):490-3. Impact Factor: 24.4. PMID: 9774279
APRIL, a New Ligand of the Tumor Necrosis Factor Family, Stimulates Tumor Cell Growth.
French LE, Hahne M, Kataoka T, Schröter M, et al.
J Exp Med. 1998; 188(6):1185-90. Impact Factor: 15.9. PMID: 9743536
Inhibition of death receptor signals by cellular FLIP.
French LE, Irmler M, Thome M, Hahne M, et al.
Nature. 1997; 388(6638):190-5. Impact Factor: 27.4. PMID: 9217161
Melanoma cell expression of Fas(Apo-1/CD95) ligand: implications for tumor immune escape.
French LE, Hahne M, Rimoldi D, Schröter M, et al.
Science. 1996; 274(5291):1363-6. Impact Factor: 23.6. PMID: 8910274
Fas and Fas ligand in embryo’s and adult mice: ligand expression in several immune-privileged tissues and co-Expression in adult tissues characterized by apoptotic cell turnover.
French LE, Hahne M, Viard I, et al.
J Cell Biol. 1996; 133(2):335-43. PMID: 8609166
Human clusterin gene expression is confined to surviving cells during in vitro programmed cell death.
French LE, Wohlwend A, Sappino AP, Tschopp J, Schifferli JA.
J Clin Invest. 1994; 93(2):877-84. Impact Factor: 8.5. PMID: 8113419
Murine clusterin: molecular cloning and mRNA localization of a gene associated with epithelial differentiation processes during embryogenesis.
French, LE, Chonn, A, Ducrest, D, Baumann, B, Belin, D, Wohlwend, A, Schifferli, JA.
The Journal of Cell Biology.1993; 122(5), 1119-30. Impact Factor: 11.7. PMID: 8354695
Distinct sites of production and deposition of the putative cell death marker clusterin in the human thymus.
French LE, Sappino AP, Tschopp J, Schifferli JA.
J Clin Invest. 1992; 90(5):1919-25. Impact Factor: 8.4. PMID: 1430214
Book
Adverse Cutaneous Drug Eruptions
French LE, Editor.
Karger Books “Chemical Immunology and Allergology”. Vol. 97, (240 p., 43 fig., 30 in color, 34 tab., hard cover), 2012. DOI: 10.1159/isbn.978-3-8055-9971-9 www.karger.com/Book/Home/256747
Books chapters
Stevens-Johnson syndrome and toxic epidermal necrolysis.
Harr T, French LE.
(2012) Chem Immunol Allergy. 97:149-66.
Erythema Multiforme, Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis.
French LE, Prins C.
(2012) Chapter 20, 319-333, in Dermatology, 3rd Ed., by Bolognia, Jorizzo and Schaffer. Ed.: Mosby.
Erythème polymorphe syndrome de Stevens-Johnson.
French LE, Saurat JH.
(2009) Chapitre 6.5, 317-320, dans Dermatologie et maladies sexuellement transmissibles (5e édition) par Saurat, Grosshans, Laugier et Lachapelle. Ed.: Masson.
Nécrolyse épidermique toxique (syndrome de Leyll).
French LE, Saurat JH.
(2009) Chapitre 6.6, 321-323, dans Dermatologie et maladies sexuellement transmissibles (5e edition) par Saurat, Grosshans, Laugier et Lachapelle. Ed. : Masson.
Erythema Multiforme, Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis.
French LE, Prins C.
(2008) Chapter 21, 287-300 in Dermatology, 2nd Ed., by Bolognia, Jorizzo and Rapini. Ed.: Mosby.
Erythème polymorphe et syndrome de Stevens-Johnson.
French LE, Saurat JH.
(2004) Chapitre 6.5, 318-323, dans Dermatologie et maladies sexuellement transmissibles (4e édition) par Saurat, Grosshans, Laugier et Lachapelle. Ed.: Masson.
Techniques de biologie moléculaire utilisées pour le diagnostic des maladies cutanées.
French LE, Saurat JH.
(2004) Chapitre 1.3, 38-39, dans Dermatologie et maladies sexuellement transmissibles (4e édition) par Saurat, Grosshans, Laugier et Lachapelle. Ed.: Masson.
Toxic epidermal necrolysis.
French LE, Prins C.
(2003) Chapter 22, 323-333, in Dermatology by Bolognia, Jorizzo and Rapini. Ed.: Mosby.
Techniques de biologie moléculaire utilisées pour le diagnostic des maladies cutanées.
French LE, Saurat JH.
(1999) Chapitre 1, 26-28, dans Dermatologie et maladies sexuellement transmissibles (3e édition) par Saurat, Grosshans, Laugier et Lachapelle. Ed.: Masson.
Infection par le virus de l’hépatite C, cryoglobulinémie et glomérulonéphrite.
Schifferli JA, French LE, Tissot JD.
(1994) Actualités Néphrologiques 1994, pp 107-128. Ed.: Flammarion Médecine-Sciences.
Structure et immunopathologie de la peau
French LE, Saurat JH.
(1992) Chapitre 43,514-523, dans Allergologie par Charpin, J, et Vervloet, D. Ed.: Flammarion Médecine-Sciences.
Selected review articles
Neutrophilic dermatoses and autoinflammatory diseases with skin involvement-innate immune disorders.
Navarini AA, Satho TK, French LE.
Semin Immunopathol, 38:45-56, 2016, Impact Factor: 7.047
Adverse cutaneous drug eruptions: current understanding.
Hoetzenecker W, Nägeli M, Mehra ET, Jensen AN, Saulite I, Schmid-Grendelmeier P, Guenova E, Cozzio A, French LE.
Semin Immunopathol, 38:75-86, 2016, Impact Factor: 7.047
The inflammasome and IL-β: implications for the treatment of inflammatory diseases.
Satoh T, Otsuka A, Contassot E, French LE.
Immunotherapy, 243-54, 2015, Impact Factor: 2.440
The inflammasomes in autoinflammatory diseases with skin involvement.
Beer HD, Contassot E, French LE.
J Invest Dermatol, 134:1805-10, 2014, Impact Factor: 6.193
New insights into acne pathogenesis: propionibacterium acnes activates the inflammasome.
Contassot E, French LE.
J Invest Dermatol, 134:310-3, 2014, Impact Factor: 6.065
The inflammasomes in autoinflammatory diseases with skin involvement.
Beer HD, Contassot E, French LE.
J Invest Dermatol, 134:1805-10, 2014, Impact Factor: 6.065
Severe cutaneous adverse reactions: acute generalized exanthematous pustulosis, toxic epidermal necrolysis and Stevens-Johnson syndrome.
Harr T, French LE.
Med Clin North, 94:727-742, 2010, Impact Factor: 2.18
Toxic epidermal necrolysis and Stevens-Johnson syndrome.
Harr T, French LE.
Orphanet J Rare Dis, 5:39, 2010, Impact Factor: 5.825
Targeting apoptosis defects in cutaneous T-cell lymphoma.
Contassot E, French LE.
J Invest Dermatol, 129:1059-1061, 2009, Impact Factor: 4.829
Lymph node tumor metastases: more susceptible than primary tumors to CD8+ T-cell immune destruction.
Contassot E, Olivier Preynat-Seauve O, French LE, Huard B.
Trends Immunol, 30:569-573, 2009, Impact Factor: 9.48
Protein-based therapeutic approaches targeting death receptors.
French LE, Tschopp J.
Cell Death Differ, 10:117-123, 2003, Impact Factor: 8.0
Defective death receptor signaling as a cause of tumor immune escape.
French LE, Tschopp J.
Semin Cancer Biol, 12:51-55, 2002, Impact Factor: 5.8
Therapeutic advances in biological response modifiers in the treatment of cutaneous t-cell lymphoma.
Vittorio CC, Rook AH, French LE, Shapiro M, Lehrer MS, Junkinshopkins JM.
BioDrugs, 15:431-437, 2001, Impact Factor: 1.9
Death receptors in cutaneous biology and disease.
Wehrli P, Viard I, Bullani R, Tschopp J, French LE.
J. Invest Dermatol, 115:141-148, 2000, Impact Factor: 4.9
Inhibition of death receptor signaling by FLICE-inhibitory protein as a
mechanism for immune escape of tumors.
French LE, Tschopp J.
J Exp Med, 190:891-894, 1999, Impact Factor: 15.3
The TRAIL to selective tumor death.
French LE, Tschopp J.
Nature Medicine, 5:146-147, 1999, Impact Factor: 27.9
Thyroiditis and hepatitis: Fas on the road to disease.
French LE, Tschopp J.
Nature Medicine, 3:387-388, 1997, Impact Factor: 27.9