Selected articles
Epidermal IL-15Rα acts as an endogenous antagonist of psoriasiform inflammation in mouse and man.
French LE, Bouchaud G, Gehrke S, Krieg C, et al.
J Exp Med. 2013; 210(10):2105-17. Impact Factor: 1.355. PMID: 24019554
The Nlrp3 inflammasome regulates acute graft-versus-host disease.
French LE, Jankovic D, Ganesan J, Bscheider M, et al.
J Exp Med. 2013; 210(10):1899-910. Impact Factor: 13.214. PMID: 23980097
Direct presentation of a melanocyte-associated antigen in peripheral lymph nodes induces cytotoxic CD8+ T cells.
French LE, Schuler P, Contassot E, Irla M, et al.
Cancer Res. 2008; 68(20):8410-8. Impact Factor: 7.7. PMID: 18922914
Resistance to FasL and TRAIL-mediated apoptosis in Sézary syndrome T-cells associated with impaired death receptor and cFLIP expression.
French LE, Contassot E, Kerl K, Roques S, et al.
Blood. 2008; 111(9):4780-7. PMID: 18314443
Extralymphatic tumors prepare draining lymph nodes to invasion via a T-cell cross-tolerance process.
French LE, Preynat-Seauve O, Contassot E, Schuler P, Piguet V, Huard B.
Cancer Res. 2007; 67(10):5009-16. Impact Factor: 8.2. PMID: 17510433
Tumor-infiltrating dendritic cells are potent antigen-presenting cells able to activate T cells and mediate tumor rejection.
French LE, Preynat-Seauve O, Schuler P, Contassot E, Beermann F, Huard B,
J Immunol. 2006; 176(1):61-7. PMID: 16365396
Impaired CD40L signaling is a cause of defective IL-12 and TNF-alpha production in Sézary syndrome: circumvention by hexameric soluble CD40L.
French LE, Huard B, Wysocka M, et al.
Blood. 2005; 105(1):219-25. Impact Factor: 10.1. PMID: 15315967
Inhibition of Toxic Epidermal Necrolysis by blockade of CD95 with Human Intravenous Immunoglobulin.
French LE, Viard I, Wehrli P, Bullani R, et al.
Science. 1998; 282(5388):490-3. Impact Factor: 24.4. PMID: 9774279
APRIL, a New Ligand of the Tumor Necrosis Factor Family, Stimulates Tumor Cell Growth.
French LE, Hahne M, Kataoka T, Schröter M, et al.
J Exp Med. 1998; 188(6):1185-90. Impact Factor: 15.9. PMID: 9743536
Inhibition of death receptor signals by cellular FLIP.
French LE, Irmler M, Thome M, Hahne M, et al.
Nature. 1997; 388(6638):190-5. Impact Factor: 27.4. PMID: 9217161
Melanoma cell expression of Fas(Apo-1/CD95) ligand: implications for tumor immune escape.
French LE, Hahne M, Rimoldi D, Schröter M, et al.
Science. 1996; 274(5291):1363-6. Impact Factor: 23.6. PMID: 8910274
Fas and Fas ligand in embryo’s and adult mice: ligand expression in several immune-privileged tissues and co-Expression in adult tissues characterized by apoptotic cell turnover.
French LE, Hahne M, Viard I, et al.
J Cell Biol. 1996; 133(2):335-43. PMID: 8609166
Human clusterin gene expression is confined to surviving cells during in vitro programmed cell death.
French LE, Wohlwend A, Sappino AP, Tschopp J, Schifferli JA.
J Clin Invest. 1994; 93(2):877-84. Impact Factor: 8.5. PMID: 8113419
Murine clusterin: molecular cloning and mRNA localization of a gene associated with epithelial differentiation processes during embryogenesis.
French, LE, Chonn, A, Ducrest, D, Baumann, B, Belin, D, Wohlwend, A, Schifferli, JA.
The Journal of Cell Biology.1993; 122(5), 1119-30. Impact Factor: 11.7. PMID: 8354695
Distinct sites of production and deposition of the putative cell death marker clusterin in the human thymus.
French LE, Sappino AP, Tschopp J, Schifferli JA.
J Clin Invest. 1992; 90(5):1919-25. Impact Factor: 8.4. PMID: 1430214
Search more on
Book
Adverse Cutaneous Drug Eruptions
French LE, Editor.
Karger Books “Chemical Immunology and Allergology”. Vol. 97, (240 p., 43 fig., 30 in color, 34 tab., hard cover), 2012. DOI: 10.1159/isbn.978-3-8055-9971-9 www.karger.com/Book/Home/256747
Books chapters
Stevens-Johnson syndrome and toxic epidermal necrolysis.
Harr T, French LE.
(2012) Chem Immunol Allergy. 97:149-66.
Erythema Multiforme, Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis.
French LE, Prins C.
(2012) Chapter 20, 319-333, in Dermatology, 3rd Ed., by Bolognia, Jorizzo and Schaffer. Ed.: Mosby.
Erythème polymorphe syndrome de Stevens-Johnson.
French LE, Saurat JH.
(2009) Chapitre 6.5, 317-320, dans Dermatologie et maladies sexuellement transmissibles (5e édition) par Saurat, Grosshans, Laugier et Lachapelle. Ed.: Masson.
Nécrolyse épidermique toxique (syndrome de Leyll).
French LE, Saurat JH.
(2009) Chapitre 6.6, 321-323, dans Dermatologie et maladies sexuellement transmissibles (5e edition) par Saurat, Grosshans, Laugier et Lachapelle. Ed. : Masson.
Erythema Multiforme, Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis.
French LE, Prins C.
(2008) Chapter 21, 287-300 in Dermatology, 2nd Ed., by Bolognia, Jorizzo and Rapini. Ed.: Mosby.
Erythème polymorphe et syndrome de Stevens-Johnson.
French LE, Saurat JH.
(2004) Chapitre 6.5, 318-323, dans Dermatologie et maladies sexuellement transmissibles (4e édition) par Saurat, Grosshans, Laugier et Lachapelle. Ed.: Masson.
Techniques de biologie moléculaire utilisées pour le diagnostic des maladies cutanées.
French LE, Saurat JH.
(2004) Chapitre 1.3, 38-39, dans Dermatologie et maladies sexuellement transmissibles (4e édition) par Saurat, Grosshans, Laugier et Lachapelle. Ed.: Masson.
Toxic epidermal necrolysis.
French LE, Prins C.
(2003) Chapter 22, 323-333, in Dermatology by Bolognia, Jorizzo and Rapini. Ed.: Mosby.
Techniques de biologie moléculaire utilisées pour le diagnostic des maladies cutanées.
French LE, Saurat JH.
(1999) Chapitre 1, 26-28, dans Dermatologie et maladies sexuellement transmissibles (3e édition) par Saurat, Grosshans, Laugier et Lachapelle. Ed.: Masson.
Infection par le virus de l’hépatite C, cryoglobulinémie et glomérulonéphrite.
Schifferli JA, French LE, Tissot JD.
(1994) Actualités Néphrologiques 1994, pp 107-128. Ed.: Flammarion Médecine-Sciences.
Structure et immunopathologie de la peau
French LE, Saurat JH.
(1992) Chapitre 43,514-523, dans Allergologie par Charpin, J, et Vervloet, D. Ed.: Flammarion Médecine-Sciences.
Selected review articles
Neutrophilic dermatoses and autoinflammatory diseases with skin involvement-innate immune disorders.
Navarini AA, Satho TK, French LE.
Semin Immunopathol, 38:45-56, 2016, Impact Factor: 7.047
Adverse cutaneous drug eruptions: current understanding.
Hoetzenecker W, Nägeli M, Mehra ET, Jensen AN, Saulite I, Schmid-Grendelmeier P, Guenova E, Cozzio A, French LE.
Semin Immunopathol, 38:75-86, 2016, Impact Factor: 7.047
The inflammasome and IL-β: implications for the treatment of inflammatory diseases.
Satoh T, Otsuka A, Contassot E, French LE.
Immunotherapy, 243-54, 2015, Impact Factor: 2.440
The inflammasomes in autoinflammatory diseases with skin involvement.
Beer HD, Contassot E, French LE.
J Invest Dermatol, 134:1805-10, 2014, Impact Factor: 6.193
New insights into acne pathogenesis: propionibacterium acnes activates the inflammasome.
Contassot E, French LE.
J Invest Dermatol, 134:310-3, 2014, Impact Factor: 6.065
The inflammasomes in autoinflammatory diseases with skin involvement.
Beer HD, Contassot E, French LE.
J Invest Dermatol, 134:1805-10, 2014, Impact Factor: 6.065
Severe cutaneous adverse reactions: acute generalized exanthematous pustulosis, toxic epidermal necrolysis and Stevens-Johnson syndrome.
Harr T, French LE.
Med Clin North, 94:727-742, 2010, Impact Factor: 2.18
Toxic epidermal necrolysis and Stevens-Johnson syndrome.
Harr T, French LE.
Orphanet J Rare Dis, 5:39, 2010, Impact Factor: 5.825
Targeting apoptosis defects in cutaneous T-cell lymphoma.
Contassot E, French LE.
J Invest Dermatol, 129:1059-1061, 2009, Impact Factor: 4.829
Lymph node tumor metastases: more susceptible than primary tumors to CD8+ T-cell immune destruction.
Contassot E, Olivier Preynat-Seauve O, French LE, Huard B.
Trends Immunol, 30:569-573, 2009, Impact Factor: 9.48
Protein-based therapeutic approaches targeting death receptors.
French LE, Tschopp J.
Cell Death Differ, 10:117-123, 2003, Impact Factor: 8.0
Defective death receptor signaling as a cause of tumor immune escape.
French LE, Tschopp J.
Semin Cancer Biol, 12:51-55, 2002, Impact Factor: 5.8
Therapeutic advances in biological response modifiers in the treatment of cutaneous t-cell lymphoma.
Vittorio CC, Rook AH, French LE, Shapiro M, Lehrer MS, Junkinshopkins JM.
BioDrugs, 15:431-437, 2001, Impact Factor: 1.9
Death receptors in cutaneous biology and disease.
Wehrli P, Viard I, Bullani R, Tschopp J, French LE.
J. Invest Dermatol, 115:141-148, 2000, Impact Factor: 4.9
Inhibition of death receptor signaling by FLICE-inhibitory protein as a
mechanism for immune escape of tumors.
French LE, Tschopp J.
J Exp Med, 190:891-894, 1999, Impact Factor: 15.3
The TRAIL to selective tumor death.
French LE, Tschopp J.
Nature Medicine, 5:146-147, 1999, Impact Factor: 27.9
Thyroiditis and hepatitis: Fas on the road to disease.
French LE, Tschopp J.
Nature Medicine, 3:387-388, 1997, Impact Factor: 27.9