Prof. Dr. sc. nat. Mitch Levesque

Prof. Dr. sc. nat. Mitch Levesque

Research groups

Dr sc. nat. Daniel Widmer
Dr sc. nat. Phil Cheng
Dr sc. nat. Ossia Eichhoff
Dr med. Verena Paulitschke
Marieke Raaijmakers
Theodora Chatziisaak
Andreas Dzung
Alice Langer
Melanie Maudrich
Mirka Schmid

Focused on

Evolution of heterogeneity

Main fields of research

We are interested in using functional genomics tools to understand the evolution of heterogeneity in skin cancer progression. In particular, we apply next-generation sequencing approaches to melanoma and other skin cancers. With access to one of the largest live-cell melanoma biobanks in the world, we have a unique resource in which to study the functional mechanisms of cellular heterogeneity and how these respond to various therapeutic regimens. Lastly, we are using the zebrafish model organism as a means to functionally validate novel genes from our genomics assays. The zebrafish is an emerging model organism that offers many advantages over traditional models according to the 3Rs (Replacement, Reduction, Refinement), and allows for a rapid functional assessment of the human cancer genome.